Not quite as straightforward as it might seem. On one hand I personally believe that Muslims -and, indeed, people of any religion- need to realise that they have no right to impose their beliefs on anyone else and so calls of blasphemy are inherently meaningless because there is no scientific/empirical proof of their beliefs just their own beliefs in them. Moreover, surely anyone secure in any of their own beliefs (religious or otherwise) should not be afraid of being challenged on them and criticism of religious beliefs should be akin to criticism of political beliefs. However, Muslims believe that to have anyone try to represent the prophet Muhammad is exceptionally disrespectful whether he is depicted as an image, sculpture or -most of all--by an actor. This is what led to the Charlie Hebdo furore with the cartoon of Muhammad. To have an actor play the prophet would then be seen as a deliberate provocation by most Muslims whereas, for example, the long history of iconization of Christ would mean that an actor playing JC would not have the same impact on most Christians.