To split hairs the quote does not refer to the side effects of mRNA vaccines being incompletely understood. It refers to the vaccinations generally.
The biochemistry of mRNA is well understood. It is a key component of every cell in every living organism.
The covid vaccines were tested in the same way as every other vaccine or drug. That involves using volunteers in a series of trails to determine that they were safe and effective. The number of people who take part in a drug trial is necessarily limited however, which means that very rare side effects might not be detected.
Very rare side effects are looked for in post rollout surveillance in which potential adverse events are reported to determine whether there is a pattern (a ‘signal’) that indicates cause as opposed to coincidence. That process worked in respect of the mRNA vaccines to suggest that they can rarely caused myocarditis and in respect of AZ to show that they can very rarely cause blood clotting.
See for example (April 2021):
https://www.ema.europa.eu/en/news/as...lood-platelets
As I mentioned, myocarditis is also a complication of covid infections (but occurring at a higher rate in the unvaccinated than the vaccinated), which suggests that it is the spike protein of the virus in the infection and that which is briefly produced within the body after an mRNA vaccine that is involved in it’s occurrence.
The clotting issue with the AZ vaccine is believed to be a consequence of a potential interaction between the virus used to deliver (‘vector’) the vaccine and a blood component called platelet factor 4.
The article concerning the post vaccination death that you linked to confirmed that there were no reports of similar incidents following Moderna vaccinations, which suggests that it may well have been a coincidental death as opposed to there being a causal link, but the report was from December 2022 and so things may have moved on.
The report also confirmed that 'complications are rare'
You seem dismissive of the need for speed. Covid was killing large numbers of people despite the lockdowns that were disrupting education, industry, regular health care and the ability of people to interact and have ‘normal’ lives. Personally, I am grateful for the speed with which the vaccines were developed and delivered.




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