Conflating several related but separate issues (the relationship being the nature of the organisations who have, for the ever-present reasons of revenue generation, been economical with the exactitude, the separation being what the various products of the pharma world have been used for), over-complicates what I was trying to say. My point regarding MMR vaccination wasn't about the efficacy of the vaccine, although I'd agree that it's a related point, nor the research effort employed over the years prior to its wide-spread introduction, it was much more simple than that.
As a direct result of mis-information spread by a supposedly respectable medical professional, who is largely responsible for the current measles epidemic amongst late-t e e n/early twenties young men and women, without question those same young people are being killed and disabled by an entirely preventable disease.
https://en.wikipedia.org/wiki/Andrew_Wakefield
Playing on the understandable fears/concerns of parents who are being asked to permit their child/children to be vaccinated is reprehensible, but was (apparently) felt to be something worth doing in order to generate his own "revenue stream".
He continues his anti-vaccine campaign, to the continued detriment of people who are being invited to take well proven, SAFE vaccines.
On the more complex, general picture you paint;
Are all vaccines safe? No. Do vaccines have side effects even when considered safe? Yes, in some circumstances (a neighbour/friend of mine was totally incapacitated for over two years, and continues to be severely limited in his mobility by the flu vaccination he had in 2017).
Do they, generally and acknowledging the risks, save lives and reduce the spread of infectious diseases, most definitely YES.
Are pharma companies saintly organisations in it for the benefit of humankind? Err, not really, but their efforts can and do result in huge benefits, as is likely if the malaria vaccine program is successful. On balance I would rather they existed, and did what they do, despite the flaws and inadequacies, (which if they put the effort in could be reduced if not eradicated by more effective government/regulatory body controls and processes) than not to exist and still be fighting out and out killers like smallpox etc.