Why I think these vaccines will not work
Peer reviewed by my looney bin friend Aid.
Imagine there's a massive room into which a load of virus bits and bobs have entered. None are exactly the same, they all have very slight mutations which might be enough to cause them to veer to the left, veer to the right or head straight on.
Back of the large room, three entrances to tunnels. A virus can only survive for so long in these tunnels before it comes out the other side and infects the host.
Tunnel A - The smallest tunnel, hard to enter but it is a shortcut to the host.
Tunnel B - Larger, but takes longer to reach the host. Many won't make it.
Tunnel C - Very large tunnel but goes round in bends and twists and takes the longest to reach the host. Very few of the virus make it through this tunnel.
The virus is observed to mostly veer to the left and enter tunnel A. This is due to evolution favouring the mutations having the most success in reaching the host quickly and being able to reproduce rapidly.
Some enter tunnel B, very very few have the robustness to survive tunnel C.
So the virus mostly going through tunnel A becomes the dominant strain.
Enter the vaccine.
Bunch of builders sent in to block tunnel A with a wooden door, they've also got panels to block as best they can tunnel B, the other tunnel is too big to block but it's not an issue with this virus. Some builders get lost and end up in the wrong room, blocking the wrong tunnels and causing clots. Most however find their way to the correct room and do the job.
Problem 1. The wood rots, the B virus gradually finds its way between the gaps, the door to tunnel A the falls off and the A virus now gets through. So we have to send in the builders again.
Problem 2. Meanwhile, because we're in a pandemic and not anticipating next year's flu, virus particles are continually entering tunnel C and now reaching the host unchallenged by the A and B virus. Virus C goes from strength to strength. The builders now have an additional problem as well as trying to maintain defences to tunnels A and B. Plus the builders who get lost end up causing more clots.
The vaccine was not designed to close tunnel C and can only shut A and B for a limited time, driving the evolution of virus C as well as now encouraging combinations of A, B and C with various degrees of robustness, speed and accuracy to find the target and reproduce.
Something like that anyway.


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